The Larne school held an event on September 30 to recognise the important milestone, with pupils also marking the occasion by burying a time capsule filled with messages in the school garden.
We’ve had a look through the archives and turned up these fab photos of events at the school through the years.
Can you spot any familiar faces?
5. Through the years
The St MacNissi's Primary School team of Niamh, Aimee, Jack and Sean who won the Larne Credit Union quiz in 2014. With them are Larne Credit Union manager Arlene Clements and classroom assistant Fiona McToal. INLT 06-373-PR Photo: P. Rippon
6. Through the years
Busy building at St MacNissi's Primary School in 2010. LT39-960-PR Photo: Peter Rippon
7. Through the years
Paul, Joel and Niamh tuck into their pancakes during the St MacNissi's Primary School Pancake Day, 2013. INLT 07-372-PR Photo: P. Rippon
8. Through the years
Dancers who joined in the St Patrick's Day celebrations in St MacNissi's Primary School, 2007. LT12-365-PR Photo: Larne Times-Peter Rippon